Trabeculectomy with ologen implant versus trabeculectomy with mitomycin-C in primary open angle glaucoma: A 2-year study

Author : Dr. Ashok Madan and Dr. Kavita Dhabarde and Dr. Karishma Shah

Aim: The aim of this study is to assess the efficacy and safety of trabeculectomy with Ologen implant versus trabeculectomy using Mitomycin-C (MMC) in patients of open-angle glaucoma. Study design- Hospital based, prospective, comparative study at a tertiary eye care centre in central India. Materials and Methods: 40 eyes of 40 patients with primary open angle glaucoma (POAG), were randomly assigned into two groups: trabeculectomy with Ologen implant (group A) or trabeculectomy with Mitomycin C (group B). Assessment of intraocular pressure (IOP), intra-operative complications, anti-glaucoma medications required post operatively was done for a period of 6 months. Results: The mean IOP in the Ologen Group was reduced to 12.89+2.43 mm Hg from 26.17 + 3.01 mm Hg and in the MMC group was reduced to 14.05+4.02 mm Hg from 26.72 + 3.067 mm Hg after 6 months. No significant inter-group difference was noticed at any visits. The complete success rate in Group A was 85% and in Group B was 80%. Conclusion: In this study, the success of trabeculectomy and complications were similar in both Ologen and MMC groups at the end of 6 months.

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