Cytotoxic Studies on Selected Siddha Plants

Author : R. Ganesan, Mathuram Venkatanarasimhan, P. Elankani, R. Shakila and Ponniahsamy

The methanolic extract of whole plant of Andrographis echioides (L.) Nees, Ocimum tenuiflorum L., Barleria prionitis L., Coldenia procumbens L. and chloroform extract of Coldenia procumbens L. were studied for the anticancer activity of the Human Ovarian Cancer Cell Line Ovkar -3 and Human Renal Cancer Cell Line 786-O in different concentrations (10,20,40 80 g/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)( Positive control compound).The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed activities of GI50 only at concentration > 80 g/ml.

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