Antiproliferative and Antioxidant potential of different extracts of Fritillaria roylei

Author : Wajaht A. Shah, Tufeel Amin Mir, Ajaz Ahmed

Fritillaria roylei is one of the medicinal plant used in traditional system of medicine for ailment of various diseases. But scientific study of the plant has been less carried out for which the study was conducted for validation of prevailing medical practice. The soxhlet extraction of the plant were conducted in various solvents (hexane, chloroform, ethyl acetate, methanol and water) differing in polarity. The phytochemical screening of extracts revealed the presence of alkaloids, saponins and tanins. In vitro Cytotoxicity evaluation against five human cancer cell lines A549 (Lung), C6 (Glioma), T47D (Breast), MCF (Breast), and TH-1(Colon) showed that the extracts of Fritillaria roylei exhibited potent cytotoxic activity. The extracts of Fritillaria roylei also showed antioxidant activity.

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