Anti urolithiatic activity of a siddha herbomineral drug by zinc implantation method in experimental rats

Author : S. Sudha Revathy, P. Suresh, M. Murugesan, K. Manickavasagam

Siddha system of medicine is one of the oldest therapeutic systems prevalent predominantly in southern part of India. Siddhars have classified diseases numbering 4448 and it is mentioned in Agasthiar rathinachurukka naadi nool. Urolithiasis refers to the formation of stones in the urinary tract. It causes pain and bleeding and may lead to secondary infection. It is the third most common affliction of the urinary tract. This study aims to evaluate the anti urolithiatic activity of the drug, Kara sooda sathu parpam by Zinc implantation method in experimental rats. The anti urolithiatic activity was studied using the zinc disc implantation method in rat model. There was a significant reduction in the stone weight in both groups treated with the drug of curative regimen when compared with the curative control group. The anti urolithiatic activity by zinc implantation method revealed that the drug is effective both in preventive and curative aspects.

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