Anti-neoplastic activities of targeted bio- moieties of Dodonaea Viscosa

Author : A.M. Krupanidhi, Prakash Dabadi, Jayamma Kulkarni, Darshan Ekbote and Prasd Davan

The objective of the present study was focused phytochemical screening of Dodonia viscosa (DV) Versatile medicinal plant. The arial parts of DV was subjected to the super critical fluid extraction (SCFE) and confirmed for the presence of many phytoconstituents like flavonoids, glycosides, saponins etc. Further the procured extract was subjected to column chromatography and isolated the active bio-compounds, those were subjected for antioxidant activity by following DPPH and SOD method. Antineoplastic activity was carried out against Erlichs Ascites Carcinoma (EAC)-induced mice. The extract and isolated bio compound showed good antioxidant and anticancer activity, however further investigations of MTT-assay is required for structural elucidation of bioactive compounds.

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