An Update on the clinical usefulness of Leptin

Author : Gandhi M and Swaminathan S

Leptin is a hormone secreted by fat cells present in adiposities and is said to play a host of useful functions in a variety of disorders like insulin resistance, dyslipidemia, hypodystrophy, lipoatrophy, hyperinsulinemia, glycemic control, obesity, weight loss and hepatic steatosis. The clinical and pharmacological usefulness of leptin has been extensively studied recently. This review article present an up-to-date research findings carried out during the last decade highlighting its usefulness in a variety of disease status such as diabetes, PCOS, Ovulatory menstruation, cancer, regulation of hepatic, kidney, cardiac, reproductive and immune functions.

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